Progressive Multifocal Leukoencephalopathy Overview

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Learn About Progressive Multifocal Leukoencephalopathy

What is the definition of Progressive Multifocal Leukoencephalopathy?
Progressive multifocal leukoencephalopathy (PML) is a neurological disorder that damages the myelin that covers and protects nerves in the white matter of the brain. It is caused by the JC virus (JCV). The disease occurs, rarely, in organ transplant patients; people undergoing chronic corticosteroid or immunosuppressive therapy; and individuals with cancer, such as Hodgkin’s disease, lymphoma, and sarcoidosis. PML is most common among individuals with acquired immune deficiency syndrome (AIDS).
What are the alternative names for Progressive Multifocal Leukoencephalopathy?
  • Progressive multifocal leukoencephalopathy
  • Leukoencephalopathy, progressive multifocal
  • PML
Who are the top Progressive Multifocal Leukoencephalopathy Local Doctors?
Advanced in Progressive Multifocal Leukoencephalopathy
Dr. Donald Negroski
Neurology
Advanced in Progressive Multifocal Leukoencephalopathy
Dr. Donald Negroski
Neurology

Negroski Neurology, Llp

5741 Bee Ridge Rd, Suite 530, 
Sarasota, FL 
 (16.8 mi)
941-487-2160
Languages Spoken:
English
See accepted insurances
Accepting New Patients

Donald Negroski is a Neurologist in Sarasota, Florida. Dr. Negroski and is rated as an Advanced provider by MediFind in the treatment of Progressive Multifocal Leukoencephalopathy. His top areas of expertise are Multiple Sclerosis (MS), Relapsing Multiple Sclerosis (RMS), Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease, and Cerebellar Degeneration. Dr. Negroski is currently accepting new patients.

Distinguished in Progressive Multifocal Leukoencephalopathy
Dr. Mary E. Shriver
Neurology
Distinguished in Progressive Multifocal Leukoencephalopathy
Dr. Mary E. Shriver
Neurology

Neurologic Care Center, P.A.

6101 Webb Rd, Suite 210, 
Tampa, FL 
 (33.3 mi)
813-249-0922
Languages Spoken:
English, Spanish
See accepted insurances
Accepting New Patients

Mary Shriver is a Neurologist in Tampa, Florida. Dr. Shriver and is rated as a Distinguished provider by MediFind in the treatment of Progressive Multifocal Leukoencephalopathy. Her top areas of expertise are Progressive Multifocal Leukoencephalopathy, Progressive Myoclonic Epilepsy, Lafora Disease, and Unverricht-Lundborg Syndrome. Dr. Shriver is currently accepting new patients.

 
 
 
 
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Advanced in Progressive Multifocal Leukoencephalopathy
Dr. Eduardo P. Palanca
Family Medicine | General Practice | Internal Medicine
Advanced in Progressive Multifocal Leukoencephalopathy
Dr. Eduardo P. Palanca
Family Medicine | General Practice | Internal Medicine

Sunstate Physicians LLC

801 W Bay Dr, Suite 321, 
Largo, FL 
 (30.5 mi)
727-316-5033
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Eduardo Palanca is a Family Medicine specialist and an Internal Medicine provider in Largo, Florida. Dr. Palanca and is rated as an Advanced provider by MediFind in the treatment of Progressive Multifocal Leukoencephalopathy. His top areas of expertise are Sepsis, Necrosis, Peptic Ulcer, Gastrostomy, and Hip Replacement. Dr. Palanca is currently accepting new patients.

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What are the latest Progressive Multifocal Leukoencephalopathy Clinical Trials?
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)
Enrollment Status: Recruiting
Publish Date: February 25, 2025

Background: - Progressive multifocal leukoencephalopathy (PML) is a severe viral infection of the brain. It is caused by JC virus. Many people have this virus in their bodies all their life, but it is usually kept in check by their immune system. If the immune system does not work right because of a disease or medication, the virus becomes active and can damage cells in the brain. Not much is known about PML ...

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A Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients With Progressive Multifocal Leukoencephalopathy
A Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients With Progressive Multifocal Leukoencephalopathy
Who is this study for: Adult patients with CACH syndrome
Enrollment Status: Recruiting
Publish Date: February 05, 2025
Intervention Type: Drug
Study Drug: NT-I7
Study Phase: Early Phase 1

Background: Progressive multifocal leukoencephalopathy (PML) is a brain infection. It is caused by a virus. PML can happen in people with a weakened immune system. PML is associated with cognitive and visual impairment as well as motor and speech disturbances. There is no treatment for PML. Researchers want to see if a new drug can help.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center