Purpura Overview
Learn About Purpura
Purpura is purple-colored spots and patches that occur on the skin, and in mucus membranes, including the lining of the mouth.
Blood spots; Skin hemorrhages
Purpura occurs when small blood vessels leak blood under the skin.
Purpura measure between 4 and 10 mm (millimeters) in diameter. When purpura spots are less than 4 mm in diameter, they are called petechiae. Purpura spots larger than 1 cm (centimeter) are called ecchymoses.
Platelets help the blood clot. A person with purpura may have a normal platelet count (non-thrombocytopenic purpuras) or a low platelet counts (thrombocytopenic purpuras).
Non-thrombocytopenic purpuras may be due to:
- Amyloidosis (disorder in which abnormal proteins build up in tissues and organs)
- Blood clotting disorders
- Congenital cytomegalovirus (condition in which an infant is infected with a virus called cytomegalovirus before birth)
- Congenital rubella syndrome
- Drugs that affect platelet function or clotting factors
- Fragile blood vessels seen in older people (senile purpura)
- Hemangioma (abnormal buildup of blood vessels in the skin or internal organs)
- Inflammation of the blood vessels (vasculitis), such as Henoch-Schönlein purpura, which causes a raised type of purpura
- Pressure changes that occur during vaginal childbirth
- Scurvy (vitamin C deficiency)
- Steroid use
- Certain infections
- Injury
Thrombocytopenic purpura may be due to:
- Drugs that reduce the platelet count
- Idiopathic thrombocytopenic purpura (ITP) -- a bleeding disorder
- Immune neonatal thrombocytopenia (can occur in infants whose mothers have ITP)
- Meningococcemia (bloodstream infection)
Call your health care provider for an appointment if you have signs of purpura.
The provider will examine your skin and ask about your medical history and symptoms, including:
- Is this the first time you have had such spots?
- When did they develop?
- What color are they?
- Do they look like bruises?
- What medicines do you take?
- What other medical problems have you had?
- Does anyone in your family have similar spots?
- What other symptoms do you have?
A skin biopsy may be done. Blood and urine tests may be ordered to determine the cause of the purpura.
Wellstar Medical Group, LLC
Jeffrey Tharp is an Internal Medicine provider in Kennesaw, Georgia. Dr. Tharp and is rated as an Experienced provider by MediFind in the treatment of Purpura. His top areas of expertise are Type 2 Diabetes (T2D), Maturity Onset Diabetes of the Young, Obesity in Children, and Hypothyroidism. Dr. Tharp is currently accepting new patients.
Mansoor Saleh is a Hematologist Oncology specialist and a Hematologist in Sandy Springs, Georgia. Dr. Saleh and is rated as a Distinguished provider by MediFind in the treatment of Purpura. His top areas of expertise are Immune Thrombocytopenic Purpura (ITP), Purpura, Adult Immune Thrombocytopenia, Thrombocytopenia, and Splenectomy.
The Emory Clinic Inc
Ana Antun is a Hematologist Oncology specialist and a Hematologist in Atlanta, Georgia. Dr. Antun and is rated as a Distinguished provider by MediFind in the treatment of Purpura. Her top areas of expertise are Thrombocytopenia, Purpura, Hemophilia A, Blood Clots, and Thrombectomy. Dr. Antun is currently accepting new patients.
Summary: To evaluate the safety and efficacy of Obinutuzumab in the treatment of pediatric primary immune thrombocytopenia in patients who have not responded adequately or relapsed after first-line glucocorticoid treatment.
Summary: To evaluate the safety and efficacy of zanubrutinib in the treatment of immune thrombocytopenia in 30 patients.
Published Date: June 07, 2023
Published By: Elika Hoss, MD, Assistant Professor of Dermatology, Mayo Clinic, Scottsdale, AZ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Dinulos JGH. Principles of diagnosis and anatomy. In: Dinulos JGH, ed. Habif's Clinical Dermatology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 1.
Kitchens CS. Purpura and other hematovascular disorders. In: Kitchens CS, Kessler CM, Konkle BA, Streiff MB, Garcia DA, eds. Consultative Hemostasis and Thrombosis. 4th ed. Philadelphia, PA: Elsevier; 2019:chap 10.