Pyogenic Liver Abscess Overview
Learn About Pyogenic Liver Abscess
Pyogenic liver abscess is a pus-filled pocket of fluid within the liver. Pyogenic means "with pus".
Liver abscess; Bacterial liver abscess; Hepatic abscess
There are many possible causes of liver abscesses, including:
- Abdominal infection, such as appendicitis, diverticulitis, or a perforated bowel
- Infection in the blood
- Infection of the tubes draining bile (bile ducts)
- Recent endoscopy of the bile draining tubes
- Trauma that damages the liver
A number of common bacteria may cause liver abscesses. In most cases, more than one type of bacteria are found.
Symptoms of liver abscess may include:
- Pain in the right upper abdomen (more common) or throughout the abdomen (less common)
- Clay-colored stools
- Dark urine
- Fever, chills, night sweats
- Loss of appetite
- Nausea, vomiting
- Unintentional weight loss
- Weakness
- Yellow skin (jaundice)
- Right shoulder pain (referred pain)
- Chest pain (lower right)
Treatment usually consists of placing a tube through the skin into the liver to drain the abscess. Less often, surgery is needed. You will also receive antibiotics for about 4 to 6 weeks. Sometimes, antibiotics alone can cure the infection.
Cedars-Sinai Medical Center
Nicholas Nissen is a General Surgeon and a Transplant Surgeon in West Hollywood, California. Dr. Nissen and is rated as a Distinguished provider by MediFind in the treatment of Pyogenic Liver Abscess. His top areas of expertise are Neuroendocrine Tumor, Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, Liver Transplant, and Pancreatectomy.
Providence Medical Foundation
Maria Stapfer is a Transplant Surgeon and a General Surgeon in Fullerton, California. Dr. Stapfer and is rated as a Distinguished provider by MediFind in the treatment of Pyogenic Liver Abscess. Her top areas of expertise are Pancreatic Cancer, Familial Pancreatic Cancer, Bile Duct Stricture, Pancreatectomy, and Hepatectomy.
Cedars-Sinai Medical Center
Kambiz Kosari is a General Surgeon and a Transplant Surgeon in West Hollywood, California. Dr. Kosari and is rated as an Advanced provider by MediFind in the treatment of Pyogenic Liver Abscess. His top areas of expertise are Acute Pancreatitis, Familial Pancreatic Cancer, Hepatitis, Liver Transplant, and Pancreatectomy.
This condition can be life threatening. The risk for death is higher in people who have many liver abscesses.
Life-threatening sepsis can develop. Sepsis is an illness in which the body has a severe inflammatory response to bacteria or other germs.
Contact your health care provider if you have:
- Any symptoms of this disorder
- Severe abdominal pain
- Confusion or decreased consciousness
- High fever that doesn't go away
- Other new symptoms during or after treatment
Prompt treatment of abdominal and other infections may reduce the risk of developing a liver abscess, but most cases are not preventable.
Summary: Pyogenic liver abscess is one of the most common visceral abscesses, its incidence is increasing worldwide. According to the previous literature, the mortality rate of pyogenic liver abscess is as high as 31% and become a serious social health problem. However, the data of prospective observational real-world studies are scarce and no relevant research of the liver histological change has been rep...
Published Date: September 10, 2022
Published By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Kim AY, Chung RT. Bacterial, parasitic, and fungal infections of the liver, including liver abscesses. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 84.
Sifri CD, Madoff LC. Infections of the liver and biliary system (liver abscess, cholangitis, cholecystitis). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 75.