Learn About Restless Legs Syndrome

What is the definition of Restless Legs Syndrome?

Restless legs syndrome (RLS) is a nervous system problem that causes you to feel an unstoppable urge to get up and pace or walk. You feel uncomfortable unless you move your legs. Moving stops the unpleasant feeling for a short time.

This disorder is also known as restless legs syndrome/Willis-Ekbom disease (RLS/WED).

What are the alternative names for Restless Legs Syndrome?

Willis-Ekbom disease; Nocturnal myoclonus; RLS; Akathisia

What are the causes of Restless Legs Syndrome?

No one knows exactly what causes RLS. It may be due to a problem with the way brain cells use dopamine. Dopamine is a brain chemical that helps with muscle movement.

RLS may be linked to some other conditions. It may occur more often in people with:

  • Chronic kidney disease
  • Diabetes
  • Iron, magnesium, or folic acid deficiency
  • Anemia (often due to iron deficiency)
  • Parkinson disease
  • Peripheral neuropathy
  • Pregnancy
  • Multiple sclerosis

RLS may also occur in people who:

  • Use certain medicines such as calcium channel blockers, lithium, or neuroleptics
  • Are stopping sedative use
  • Use caffeine, alcohol, or nicotine

RLS occurs most often in middle-aged and older adults. Women are more likely to have RLS than men.

RLS is commonly passed down in families. This may be a factor when symptoms start at a younger age.

What are the symptoms of Restless Legs Syndrome?

RLS leads to unpleasant feelings in your lower legs. These feelings cause an unstoppable urge to move your legs. You may feel:

  • Creeping and crawling
  • Bubbling, pulling, or tugging
  • Burning or searing
  • Aching, throbbing, or pain
  • Itching or gnawing
  • Tingling, pins and needles in the feet

These sensations:

  • Are worse at night when you lie down to the point that it may interfere with sleep and keep you awake
  • Sometimes occur during the day
  • Start or get worse when you lie down or sit for long periods of time
  • May last for 1 hour or longer
  • Sometimes also occur in the upper legs, feet, or arms
  • Are relieved when you move or stretch as long as you keep moving

Symptoms can make it difficult to sit during air or car travel, or through classes or meetings.

Stress or emotional upset can make symptoms worse.

Most people with RLS have rhythmic leg movements when they sleep. This condition is called periodic limb movement disorder.

All of these symptoms make it hard to sleep. Lack of sleep can lead to:

  • Daytime sleepiness
  • Anxiety or depression
  • Confusion
  • Difficulty thinking clearly
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What are the current treatments for Restless Legs Syndrome?

RLS can't be cured. However, treatment can help relieve symptoms.

Certain lifestyle changes may help you cope with the condition and ease symptoms.

  • Get enough sleep. Go to bed and wake up at the same time every day. Make sure your bed and bedroom are comfortable.
  • Try using hot or cold packs on your legs.
  • Help your muscles relax with gentle stretches, massage, and warm baths.
  • Take time out of your day to just relax. Try yoga, meditation, or other ways to ease tension.
  • Avoid caffeine, alcohol, and tobacco. They may make symptoms worse.

Your provider may prescribe medicines to treat RLS.

Some medicines help control symptoms:

  • Pramipexole (Mirapex)
  • Ropinirole (Requip)
  • Low doses of narcotics

Other medicines can help you sleep:

  • Sinemet (combination carbidopa-levodopa), an anti-Parkinson medicine
  • Gabapentin and pregabalin
  • Clonazepam or other tranquilizers

Medicines to help you sleep may cause daytime sleepiness.

Treating conditions with similar symptoms such as peripheral neuropathy or iron deficiency can also help relieve symptoms.

Who are the top Restless Legs Syndrome Local Doctors?
Neurology | Pain Medicine
Neurology | Pain Medicine

Baylor St Lukes Medical Group

17350 St Lukes Way, 
The Woodlands, TX 
 (2.6 mi)
Languages Spoken:
English, Amharic, Spanish
Accepting New Patients

Todd Maraist is a Neurologist and a Pain Medicine provider in The Woodlands, Texas. Dr. Maraist and is rated as an Advanced provider by MediFind in the treatment of Restless Legs Syndrome. His top areas of expertise are Cerebellar Degeneration, Neuronal Intranuclear Inclusion Disease (NIID), Seizures, and Autosomal Dominant Partial Epilepsy with Auditory Features. Dr. Maraist is currently accepting new patients.

Family Medicine
Family Medicine

David P Ellent PLLC

9303 Pinecroft Dr, Suite 340, 
The Woodlands, TX 
 (0.6 mi)
Languages Spoken:
English, Hindi, Spanish, Ukrainian, Urdu
Accepting New Patients
Offers Telehealth

Moiz Tajkhanji is a Family Medicine provider in The Woodlands, Texas. Dr. Tajkhanji and is rated as an Experienced provider by MediFind in the treatment of Restless Legs Syndrome. His top areas of expertise are Familial Hypertension, Hypertension, Glucocorticoid-Remediable Aldosteronism, and Diabetic Neuropathy. Dr. Tajkhanji is currently accepting new patients.

 
 
 
 
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Neurology | Neuroradiology
Neurology | Neuroradiology

Mhs Physicians Of Texas

9180 Pinecroft Dr, Suite 500, 
Shenandoah, TX 
 (0.8 mi)
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Philip Blum is a Neurologist and a Neuroradiologist in Shenandoah, Texas. Dr. Blum and is rated as an Experienced provider by MediFind in the treatment of Restless Legs Syndrome. His top areas of expertise are Chronic Inflammatory Demyelinating Polyneuropathy, Memory Loss, Spinal Muscular Atrophy (SMA), and Seizures. Dr. Blum is currently accepting new patients.

What is the outlook (prognosis) for Restless Legs Syndrome?

RLS is not dangerous. However, it can be uncomfortable, making it hard to sleep and affecting your quality of life.

What are the possible complications of Restless Legs Syndrome?

You may not be able to sleep well (insomnia).

When should I contact a medical professional for Restless Legs Syndrome?

Contact your provider for an appointment if:

  • You have symptoms of RLS
  • Your sleep is disrupted
  • Symptoms get worse
How do I prevent Restless Legs Syndrome?

There is no way to prevent RLS.

What are the latest Restless Legs Syndrome Clinical Trials?
Targeting Dopamine-Mediated Social Reward Sensitivity to Remediate Social Disconnection

Summary: This study seeks to understand if the medication pramipexole improves social connectedness and functioning in adults (ages 18-50) who experience anxiety or depression. The study plans to enroll 108 participants total across two sites (University of California San Diego and New York State Psychiatric Institute). Pramipexole will be given in a 6-week randomized, double-blind, placebo-controlled tria...

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Restless Leg Syndrome: Is There a Response to Buddhist Walking Meditation in Hemodialysis

Summary: the restless leg syndrome is a common complaint in person who undergo hemodialysis. Buddhist walking meditation efficacy was not investigated in those population

Who are the sources who wrote this article ?

Published Date: August 28, 2023
Published By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 09/06/2024.

What are the references for this article ?

Allen RP, Montplaisir J, Walters AS, Hogl B, Ferini-Strambi L. Restless legs syndrome (Willis-Ekbom disease) and periodic limb movements during sleep. In: Kryger M, Roth T, Goldstein CA, Dement WC, eds. Principles and Practice of Sleep Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 121.

Avidan AY. Sleep and its disorders. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 101.

National Institute of Neurological Disorders and Stroke website. Restless legs syndrome. www.ninds.nih.gov/health-information/disorders/restless-legs-syndrome. Updated July 19, 2024. Accessed September 6, 2024.

Winkelman JW, Armstrong MJ, Allen RP, et al. Practice guideline summary: treatment of restless legs syndrome in adults: report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2016;87(24):2585-2593. PMID: 27856776 pubmed.ncbi.nlm.nih.gov/27856776/.