Sea-Blue Histiocytosis Overview

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Learn About Sea-Blue Histiocytosis

What is the definition of Sea-Blue Histiocytosis?
Sea-Blue histiocytosis, also known as inherited lipemic splenomegaly, is an extremely rare condition characterized by elevated triglyceride levels (hypertriglyceridemia) and an enlarged spleen (splenomegaly). The disorder is so named because certain white blood cells, known as histiocytes, appear bright blue when stained and viewed under the microscope. Additional signs and symptoms may include a low platelet count (thrombocytopenia), liver function abnormalities, and heart disease. It is one of a group of related fat (lipid) disorders caused by certain changes in the APOE gene. The genetic change associated with this condition is inherited in an autosomal dominant manner though other factors, such as a patient's gender, the patient's lipid levels, and the genetic makeup of the other APOE gene may play a role in how the condition is expressed.
What are the alternative names for Sea-Blue Histiocytosis?
  • Sea-Blue histiocytosis
  • Histiocytosis, sea-blue
  • Inherited Lipemic Splenomegaly
  • Sea-Blue histiocyte disease
Who are the top Sea-Blue Histiocytosis Local Doctors?
Dr. Sumeet Bhatia
Oncology | Hematology | Hematology Oncology
Dr. Sumeet Bhatia
Oncology | Hematology | Hematology Oncology

Community Physicians Of Indiana Inc

7229 Clearvista Dr, Symptom Management Group, 
Indianapolis, IN 
 (78.9 mi)
317-621-4300
Languages Spoken:
English
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Sumeet Bhatia is an Oncologist and a Hematologist in Indianapolis, Indiana. Dr. Bhatia and is rated as an Advanced provider by MediFind in the treatment of Sea-Blue Histiocytosis. His top areas of expertise are Small Cell Lung Cancer (SCLC), Lung Adenocarcinoma, Neuroendocrine Tumor, Bone Marrow Aspiration, and Gastrostomy. Dr. Bhatia is currently accepting new patients.

Dr. Naveen Manchanda
Hematology | Hematology Oncology | Oncology
Dr. Naveen Manchanda
Hematology | Hematology Oncology | Oncology

University Medical Diagnostic Associates Inc

550 N University Blvd, 
Indianapolis, IN 
 (69.2 mi)
217-274-5000
Languages Spoken:
English
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Accepting New Patients

Naveen Manchanda is a Hematologist and a Hematologist Oncology provider in Indianapolis, Indiana. Dr. Manchanda and is rated as an Experienced provider by MediFind in the treatment of Sea-Blue Histiocytosis. His top areas of expertise are Sickle Cell Disease, Deep Vein Thrombosis, Atypical Hemolytic Uremic Syndrome (aHUS), D-Plus Hemolytic Uremic Syndrome, and Bone Marrow Aspiration. Dr. Manchanda is currently accepting new patients.

 
 
 
 
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Dr. Jennifer K. Morgan
Oncology | Hematology
Dr. Jennifer K. Morgan
Oncology | Hematology

Indiana University Health Inc

6845 Rama Dr, 
Indianapolis, IN 
 (76.1 mi)
317-962-9000
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

Jennifer Morgan is an Oncologist and a Hematologist in Indianapolis, Indiana. Dr. Morgan and is rated as an Experienced provider by MediFind in the treatment of Sea-Blue Histiocytosis. Her top areas of expertise are Inflammatory Breast Cancer, Paget Disease of the Breast, Deep Vein Thrombosis, and Familial Colorectal Cancer. Dr. Morgan is currently accepting new patients.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center