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Learn About Sengers Syndrome

View Main Condition: Cardiomyopathy

What is the definition of Sengers Syndrome?
Sengers syndrome is a rare autosomal recessive mitochondrial (cells that create energy) depletion disorder that causes a loss of function of the acylglycerol kinase (AGK) gene that is responsible for maintaining mitochondrial DNA, resulting in infants that are born with congenital cataracts, hypertrophic cardiomyopathy (thickening of heart muscle; HOCM), skeletal myopathy, and lactic acidosis.
What are the symptoms of Sengers Syndrome?
The hallmark symptom of Sengers syndrome is the appearance of congenital cataracts in an infant in the first few weeks of life, along with the development of progressive hypertrophic cardiomyopathy (thickening of heart muscle and heart failure), skeletal myopathy, and lactic acidosis. Additional symptoms may include generalized hypotonia (lack of muscle tone), exercise intolerance, and delayed motor development. Some children with Sengers syndrome may have mental retardation.
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What are the current treatments for Sengers Syndrome?
If untreated, the progressive hypertrophic cardiomyopathy associated with Sengers syndrome can be fatal in the first few weeks of life. Some patients may be treated with heart transplantation. The cataracts associated with Sengers syndrome may require surgical removal. Children with Sengers syndrome may have normal mental development if the lactic acidosis is treated with oxygen and intravenous fluids.
Who are the top Sengers Syndrome Local Doctors?

Licking Memorial Professional Corporation

1320 W Main St, 
Newark, OH 
 24.5 mi
Accepting New Patients

Fikadu Tekleyes is a Cardiologist in Newark, Ohio. Dr. Tekleyes and is rated as an Experienced provider by MediFind in the treatment of Sengers Syndrome. His top areas of expertise are Atrial Fibrillation, Pulmonary Edema, Heart Failure, and Heart Murmurs. Dr. Tekleyes is currently accepting new patients.

Ohiohealth Corporation

600 N Pickaway St, 
Circleville, OH 
 19.4 mi
Accepting New Patients
Offers Telehealth

Gregory Lam is a Cardiologist in Circleville, Ohio. Dr. Lam and is rated as an Experienced provider by MediFind in the treatment of Sengers Syndrome. His top areas of expertise are Aortic Regurgitation, Necrosis, Pediatric Myocarditis, and Atrial Fibrillation. Dr. Lam is currently accepting new patients.

 
 
 
 
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Cardiac Electrophysiology | Cardiology
Cardiac Electrophysiology | Cardiology

Mount Carmel Healthproviders Two LLC

85 Mcnaughten Rd, 
Columbus, OH 
 22.2 mi
Accepting New Patients

Jianqing Li is a Cardiac Electrophysiologist and a Cardiologist in Columbus, Ohio. Dr. Li and is rated as an Experienced provider by MediFind in the treatment of Sengers Syndrome. Her top areas of expertise are Arrhythmias, Atrial Fibrillation, Sick Sinus Syndrome, Pacemaker Implantation, and Cardiac Ablation. Dr. Li is currently accepting new patients.

What are the latest Sengers Syndrome Clinical Trials?
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What are the Latest Advances for Sengers Syndrome?

There is no recent research available for this condition. Please check back because thousands of new papers are published every week and we strive to find and display the most recent relevant research as soon as it is available.