Spastic Paraplegia Type 2 Latest Advances

DDHD2 possesses both lipase and transacylase capacities that remodel triglyceride acyl chains.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 20, 2025

Clinical characteristics and genetic study of a child with Spastic paraplegia 52 due to variant of AP4S1 gene and a literature review

Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

Published: November 13, 2025

Nutritional Approaches in Neurodegenerative Disorders: A Mini Scoping Review with Emphasis on SPG11-Related Conditions.

Journal: Nutrients

Published: September 24, 2025

Botulinum Toxin Treatment in Hereditary Spastic Paraplegia-A Comprehensive Review and Update.

Journal: Toxins

Published: September 04, 2025

The Impact of VAMP1 Mutations on Synaptic Vesicle Fusion Dynamics in Familial Spastic Disorders.

Journal: Journal of child neurology

Published: August 26, 2025

The hereditary spastic paraplegia type 21 (SPG21) protein is a RAB7A effector that promotes noncanonical mTORC1-catalyzed TFEB phosphorylation and cytoplasmic retention.

Journal: Molecular biology of the cell

Published: August 20, 2025

A case of hereditary spastic paraplegia type 64 with ENTPD1 gene variant

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics

Published: August 20, 2025

4-Phenylbutyric Acid Improves Gait Ability of UBAP1-Related Spastic Paraplegia Mouse Model: Therapeutic Potential for SPG80.

Journal: International journal of molecular sciences

Published: August 14, 2025

Fluid Biomarkers in Hereditary Spastic Paraplegia: A Narrative Review and Integrative Framework for Complex Neurodegenerative Mechanisms.

Journal: Genes

Published: August 07, 2025

Novel missense ALDH18A1 variant in a family with autosomal dominant spastic paraplegia.

Journal: Journal of neurology

Published: August 02, 2025

Wings of Discovery: Using Drosophila to Decode Hereditary Spastic Paraplegia and Ataxias.

Journal: Cells

Published: July 28, 2025

Expanding the Phenotypic Spectrum of SPG4: Autism Spectrum Disorder in Early-Onset and Complex SPAST-HSP and Case Study.

Journal: Genes

Published: July 17, 2025

Filters

DDHD2 possesses both lipase and transacylase capacities that remodel triglyceride acyl chains.

DDHD2 possesses both lipase and transacylase capacities that remodel triglyceride acyl chains.

Clinical characteristics and genetic study of a child with Spastic paraplegia 52 due to variant of AP4S1 gene and a literature review

Clinical characteristics and genetic study of a child with Spastic paraplegia 52 due to variant of AP4S1 gene and a literature review

Nutritional Approaches in Neurodegenerative Disorders: A Mini Scoping Review with Emphasis on SPG11-Related Conditions.

Nutritional Approaches in Neurodegenerative Disorders: A Mini Scoping Review with Emphasis on SPG11-Related Conditions.

Botulinum Toxin Treatment in Hereditary Spastic Paraplegia-A Comprehensive Review and Update.

Botulinum Toxin Treatment in Hereditary Spastic Paraplegia-A Comprehensive Review and Update.

The Impact of VAMP1 Mutations on Synaptic Vesicle Fusion Dynamics in Familial Spastic Disorders.

The Impact of VAMP1 Mutations on Synaptic Vesicle Fusion Dynamics in Familial Spastic Disorders.

The hereditary spastic paraplegia type 21 (SPG21) protein is a RAB7A effector that promotes noncanonical mTORC1-catalyzed TFEB phosphorylation and cytoplasmic retention.

The hereditary spastic paraplegia type 21 (SPG21) protein is a RAB7A effector that promotes noncanonical mTORC1-catalyzed TFEB phosphorylation and cytoplasmic retention.

A case of hereditary spastic paraplegia type 64 with ENTPD1 gene variant

A case of hereditary spastic paraplegia type 64 with ENTPD1 gene variant

4-Phenylbutyric Acid Improves Gait Ability of UBAP1-Related Spastic Paraplegia Mouse Model: Therapeutic Potential for SPG80.

4-Phenylbutyric Acid Improves Gait Ability of UBAP1-Related Spastic Paraplegia Mouse Model: Therapeutic Potential for SPG80.

Fluid Biomarkers in Hereditary Spastic Paraplegia: A Narrative Review and Integrative Framework for Complex Neurodegenerative Mechanisms.

Fluid Biomarkers in Hereditary Spastic Paraplegia: A Narrative Review and Integrative Framework for Complex Neurodegenerative Mechanisms.

Novel missense ALDH18A1 variant in a family with autosomal dominant spastic paraplegia.

Novel missense ALDH18A1 variant in a family with autosomal dominant spastic paraplegia.

Wings of Discovery: Using Drosophila to Decode Hereditary Spastic Paraplegia and Ataxias.

Wings of Discovery: Using Drosophila to Decode Hereditary Spastic Paraplegia and Ataxias.

Expanding the Phenotypic Spectrum of SPG4: Autism Spectrum Disorder in Early-Onset and Complex SPAST-HSP and Case Study.

Expanding the Phenotypic Spectrum of SPG4: Autism Spectrum Disorder in Early-Onset and Complex SPAST-HSP and Case Study.