Supranuclear Ophthalmoplegia Overview
Learn About Supranuclear Ophthalmoplegia
Supranuclear ophthalmoplegia is a condition that affects the movement of the eyes.
Progressive supranuclear palsy - supranuclear ophthalmoplegia; Encephalitis - supranuclear ophthalmoplegia; Olivopontocerebellar atrophy - supranuclear ophthalmoplegia; Amyotrophic lateral sclerosis - supranuclear ophthalmoplegia; Whipple disease - supranuclear ophthalmoplegia; Dementia - supranuclear ophthalmoplegia
This disorder occurs because the brain is sending and receiving faulty information through the nerves that control eye movement. The nerves themselves are healthy.
People who have this problem often have progressive supranuclear palsy (PSP). This is a disorder that affects the way the brain controls movement, including eye movement.
Other disorders that have been associated with this condition include:
- Inflammation of the brain (encephalitis)
- Disease that causes areas deep in the brain, just above the spinal cord, to shrink (olivopontocerebellar atrophy)
- Disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement (for example, amyotrophic lateral sclerosis)
- Condition that also causes malabsorption disorder of the small intestine as well as other symptoms (Whipple disease)
People with supranuclear ophthalmoplegia are unable to move their eyes at will in all directions, especially looking upward.
Depending on what condition may be causing the supranuclear ophthalmoplegia, associated symptoms may include:
- Mild dementia
- Stiff and uncoordinated movements like those of Parkinson disease
- Symptoms of disorders associated with supranuclear ophthalmoplegia
Treatment depends on the cause and symptoms of the supranuclear ophthalmoplegia.
Matthias Brendel practices in Munich, Germany. Mr. Brendel is rated as an Elite expert by MediFind in the treatment of Supranuclear Ophthalmoplegia. His top areas of expertise are Progressive Supranuclear Palsy, Progressive Supranuclear Palsy Atypical, Supranuclear Ophthalmoplegia, and Brown Syndrome.
Duke Neurology Morreene Road
Kyle Mitchell is a Neurologist in Durham, North Carolina. Dr. Mitchell is rated as a Distinguished provider by MediFind in the treatment of Supranuclear Ophthalmoplegia. His top areas of expertise are Progressive Supranuclear Palsy, Supranuclear Ocular Palsy, Progressive Supranuclear Palsy Atypical, Supranuclear Ophthalmoplegia, and Deep Brain Stimulation. Dr. Mitchell is currently accepting new patients.
Duke Neurology Morreene Road
Sneha Mantri is a Neurologist in Durham, North Carolina. Dr. Mantri is rated as a Distinguished provider by MediFind in the treatment of Supranuclear Ophthalmoplegia. Her top areas of expertise are Parkinson's Disease, Movement Disorders, Supranuclear Ophthalmoplegia, Progressive Supranuclear Palsy, and Deep Brain Stimulation. Dr. Mantri is currently accepting new patients.
Outlook depends on the cause of the supranuclear ophthalmoplegia.
Summary: This study is designed to learn more about overall tau burden in the brain of patients with Progressive Supranuclear Palsy (PSP).
Summary: The objective of this proposal is to investigate the effect of non-invasive repetitive cerebellar transcranial magnetic stimulation (rTMS) on motor control in progressive supranuclear (PSP). The central hypothesis is that augmenting cerebellar inhibition via cerebellar rTMS will decrease postural instability in patients with PSP. We will use functional near infrared spectroscopy (fNIRS) to examine...
Published Date: June 13, 2024
Published By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Lavin PJM, Donahue SP, Longmuir RA. Disorders of supranuclear control of ocular motility. In: Yanoff M, Duker JS, eds. Ophthalmology. 6th ed. Philadelphia, PA: Elsevier; 2023:chap 9.14.
Lin CR. Progressive supranuclear palsy. In: Ferri FF, ed. Ferri's Clinical Advisor 2025. Philadelphia, PA: Elsevier; 2025:chap 918.e4-918e6.
Ling H. Clinical approach to progressive supranuclear palsy. J Mov Disord. 2016;9(1):3-13. PMID: 26828211 www.pubmed.ncbi.nlm.nih.gov/26828211/.
Rucker JC, Lavin PJM. Neuro-ophthalmology: ocular motor system. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 18.


