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Learn About Urothelial Cancer

What is the definition of Urothelial Cancer?
Urothelial cancer, also known as transitional cell carcinoma, affects the kidney (renal) pelvis or ureter (tube) that drains urine from the kidney to the bladder and/or the lining of the inside of the bladder. It is the most common form of bladder cancer and occurs more frequently in men and older adults. The cause of urothelial cancer is unknown; however, some suspected causes are chronic irritation of the kidney from pain medicines, exposure to manufacturing chemicals and dyes, smoking or other tobacco use, past radiation exposure, and parasitic infections.
What are the symptoms of Urothelial Cancer?
Symptoms of urothelial cancer include fatigue, unexplained weight loss, loss of appetite, anemia, constant back pain, flank pain, pelvic pain, urinary urgency, pain, burning, or discomfort when urinating, or blood in urine (hematuria).
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What are the current treatments for Urothelial Cancer?
Treatment for urothelial cancer includes surgery and chemotherapy. Bladder cancer can recur after treatment; therefore, long-term follow-up is necessary.
Who are the top Urothelial Cancer Local Doctors?

Michigan Institute Of Urology

1701 East South Blvd., Suite 340, 
Rochester Hills, MI 
 22.6 mi
Accepting New Patients
Offers Telehealth

Brian Seifman is an Urologist in Rochester Hills, Michigan. Dr. Seifman and is rated as a Distinguished provider by MediFind in the treatment of Urothelial Cancer. His top areas of expertise are Renal Cell Carcinoma (RCC), Congenital Mesoblastic Nephroma, Prostate Cancer, Ureteroscopy, and Lithotripsy. Dr. Seifman is currently accepting new patients.

Michigan Institute Of Urology

130 Town Center Drive, Suite 101, 
Troy, MI 
 22.3 mi
Accepting New Patients

Kenneth Kernen is an Urologist in Troy, Michigan. Dr. Kernen and is rated as a Distinguished provider by MediFind in the treatment of Urothelial Cancer. His top areas of expertise are Prostate Cancer, Familial Prostate Cancer, Enlarged Prostate (BPH), Nephrectomy, and Reconstructive Urology Surgery. Dr. Kernen is currently accepting new patients.

 
 
 
 
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Michigan Institute Of Urology

130 Town Center Drive, Suite 101, 
Troy, MI 
 22.3 mi
Accepting New Patients
Offers Telehealth

Jason Hafron is an Urologist in Troy, Michigan. Dr. Hafron and is rated as a Distinguished provider by MediFind in the treatment of Urothelial Cancer. His top areas of expertise are Prostate Cancer, Familial Prostate Cancer, Renal Cell Carcinoma (RCC), Prostatectomy, and Ureteroscopy. Dr. Hafron is currently accepting new patients.

What are the latest Urothelial Cancer Clinical Trials?
A Phase II Study of Ipilimumab, Cabozantinib, and Nivolumab in Rare Genitourinary Cancers (ICONIC)

Summary: This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as ...

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A Phase III Randomized Trial of Eribulin (NSC #707389) With Gemcitabine Versus Standard of Care (Physician's Choice) for Treatment of Metastatic Urothelial Carcinoma Refractory to, or Ineligible for, Anti PD1/PDL1 Therapy

Summary: This phase III trial compares the usual chemotherapy treatment to eribulin plus gemcitabine in treating patients with urothelial cancer that has spread to other places in the body (metastatic). Chemotherapy drugs, such as eribulin, gemcitabine, docetaxel, paclitaxel, and sacituzumab govitecan work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them fr...

What are the Latest Advances for Urothelial Cancer?
A case of undifferentiated carcinoma of the bladder treated by combination therapy of surgery, local radiation, and immune checkpoint inhibitors.
Curative effect of complete transperitoneal laparoscopic nephroureterectomy in post kidney transplantation patients with upper tract urothelial carcinoma.
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