WAGR Syndrome Overview
Learn About WAGR Syndrome
WAGR syndrome is a disorder that affects many body systems and is named for its main features: Wilms tumor, aniridia, genitourinary anomalies, and a range of developmental delays.
WAGR syndrome is caused by a deletion of genetic material on the short (p) arm of chromosome 11. The size of the deletion varies among affected individuals.
The prevalence of WAGR syndrome ranges from 1 in 500,000 to 1 million individuals. It is estimated that one-third of people with aniridia actually have WAGR syndrome. Approximately 7 in 1,000 cases of Wilms tumor can be attributed to WAGR syndrome.
Most cases of WAGR syndrome are not inherited. They are caused by a chromosomal deletion that occurs randomly during the formation of reproductive cells (eggs or sperm) or in early fetal development. Affected people typically have no history of the disorder in their family.
Endwell Family Physicians Llp
Jonathan Harris is a Family Medicine provider in Endwell, New York. Dr. Harris and is rated as an Experienced provider by MediFind in the treatment of WAGR Syndrome. His top areas of expertise are Cirrhosis, Hypertension, Glucocorticoid-Remediable Aldosteronism, and Familial Hypertension.
Our Lady Of Lourdes Memorial Hospital Inc
Marek Gawel is an Internal Medicine provider in Binghamton, New York. Dr. Gawel and is rated as an Experienced provider by MediFind in the treatment of WAGR Syndrome. His top areas of expertise are Grass Allergy, High Cholesterol, Glucocorticoid-Remediable Aldosteronism, and Hypertension.
Geisinger Clinic
Michael Ramsey is a Dermatologist in Danville, Pennsylvania. Dr. Ramsey and is rated as an Advanced provider by MediFind in the treatment of WAGR Syndrome. His top areas of expertise are Basal Cell Skin Cancer, Squamous Cell Skin Carcinoma, Head and Neck Squamous Cell Carcinoma (HNSCC), and Bowen's Disease.
Summary: Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease (AD)/age-related dementias (ARD). Participants: Participants include 120 adults with ID, their caregivers, and their coaches (up to 360 individual participants, grouped as triads), recr...
Summary: CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, in...
Published Date: June 28, 2023
Published By: National Institutes of Health