Learn About Xanthoma

What is the definition of Xanthoma?

Xanthoma is a skin condition in which certain fats build up under the surface of the skin.

What are the alternative names for Xanthoma?

Skin growths - fatty; Xanthelasma

What are the causes of Xanthoma?

Xanthomas are common, especially among older adults and people with high blood lipids (fats). Xanthomas vary in size. Some are very small. Others are bigger than 3 inches (7.5 centimeters) in diameter. They may appear anywhere on the body. But, they are most often seen on the elbows, joints, tendons, knees, hands, feet, or buttocks.

Xanthomas may be a sign of a medical condition that involves an increase in blood lipids. Such conditions include:

  • Certain cancers
  • Diabetes
  • High blood cholesterol levels
  • Inherited metabolic disorders, such as familial hypercholesterolemia
  • Scarring of the liver due to blocked bile ducts (primary biliary cirrhosis)
  • Inflammation and swelling of the pancreas (pancreatitis)
  • Underactive thyroid (hypothyroidism)

Xanthelasma palpebra is a common type of xanthoma that appears on the eyelids. It usually occurs without any underlying medical condition.

What are the symptoms of Xanthoma?

A xanthoma looks like a yellow to orange bump (papule) with defined borders. There may be several individual ones or they may form clusters.

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What are the current treatments for Xanthoma?

If you have a disease that causes increased blood lipids, treating the condition may help reduce the development of xanthomas.

If the growth bothers you, your provider may remove it by surgery or with a laser. However, xanthomas may come back after surgery.

Who are the top Xanthoma Local Doctors?
Experienced in Xanthoma
Internal Medicine
Experienced in Xanthoma
Internal Medicine

TruHealthNow

22000 Dulles Retail Plz, 
Sterling, VA 
 (3.7 mi)
Experience:
40+ years
Languages Spoken:
English, Spanish
Accepting New Patients
Offers Telehealth

James Cleveland is an Internal Medicine provider in Sterling, Virginia. Dr. Cleveland has been practicing medicine for over 40 years and is rated as an Experienced provider by MediFind in the treatment of Xanthoma. His top areas of expertise are Parainfluenza, Parainfluenza Virus Type 3, Vitamin D Deficiency, and Familial Hypertension. Dr. Cleveland is currently accepting new patients.

Experienced in Xanthoma
Family Medicine | Geriatrics
Experienced in Xanthoma
Family Medicine | Geriatrics

Inova Physician Partners LLC

381 Elden St, 1000 Herndon Family Medicine, 
Herndon, VA 
 (0.6 mi)
Languages Spoken:
English, German
Accepting New Patients
Offers Telehealth

Deborah Leavens is a Family Medicine specialist and a Geriatrics provider in Herndon, Virginia. Dr. Leavens and is rated as an Experienced provider by MediFind in the treatment of Xanthoma. Her top areas of expertise are Primary Intestinal Lymphangiectasia, Meige Disease, Lymphangiectasis, and Osteoporosis. Dr. Leavens is currently accepting new patients.

 
 
 
 
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Experienced in Xanthoma
Family Medicine
Experienced in Xanthoma
Family Medicine

Inova Physician Partners LLC

381 Elden St, 1000 Herndon Family Medicine, 
Herndon, VA 
 (0.6 mi)
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Marc Plescia is a Family Medicine provider in Herndon, Virginia. Dr. Plescia and is rated as an Experienced provider by MediFind in the treatment of Xanthoma. His top areas of expertise are Melorheostosis with Osteopoikilosis, Melorheostosis, Osteopenia, and Peyronie Disease. Dr. Plescia is currently accepting new patients.

What is the outlook (prognosis) for Xanthoma?

The growth is noncancerous and painless, but it may be a sign of another medical condition.

When should I contact a medical professional for Xanthoma?

Call your provider if xanthomas develop. They may indicate an underlying disorder that needs treatment.

How do I prevent Xanthoma?

To reduce the development of xanthomas, you may need to control your blood triglyceride and cholesterol levels.

What are the latest Xanthoma Clinical Trials?
Disease Pathogenesis and Natural History of Lipid Disorders

Summary: This study will evaluate people with dyslipidemias - disorders that affect the fat content in the blood. Fats, or lipids, such as cholesterol and triglycerides, are carried in the blood in particles called lipoproteins. These particles are involved in causing blood vessel diseases that can lead to conditions like atherosclerosis (hardening of the arteries) or heart attack. Participants will underg...

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International Rare Histiocytic Disorders Registry (IRHDR)

Summary: The rare histiocytic disorders (RHDs) are characterized by the infiltration of one or more organs by non-LCH histiocytes. They can range from localized disease that resolves spontaneously, to progressive disseminated forms that can be sometimes life-threatening. Since they are extremely rare, there is limited understanding of their causes and best treatment options. Physicians, patients and parent...

What are the Latest Advances for Xanthoma?
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Juvenile Xanthoma.
Who are the sources who wrote this article ?

Published Date: May 31, 2023
Published By: Ramin Fathi, MD, FAAD, Director, Phoenix Surgical Dermatology Group, Phoenix, AZ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Dinulos JGH. Cutaneous manifestations of internal disease. In: Dinulos JGH, ed. Habif's Clinical Dermatology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 26.

Massengale WT. Xanthomas. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 4th ed. Philadelphia, PA: Elsevier; 2018:chap 92.

White LE, Horenstein MG, Shea CR. Xanthomas. In: Lebwohl MG, Heymann WR, Coulson IH, Murrell DF, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. 6th ed. Philadelphia, PA: Elsevier; 2022:chap 256.