Acute Myeloid Leukemia (AML) Overview

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Learn About Acute Myeloid Leukemia (AML)

View Main Condition: Leukemia

What is the definition of Acute Myeloid Leukemia (AML)?
Acute myeloid leukemia (AML) is a cancer that affects the blood and bone marrow. Conditions are generally called "acute" when they develop quickly and have an aggressive course. The signs and symptoms of AML vary but may include easy bruising; bone pain or tenderness; fatigue; fever; frequent nosebleeds; bleeding from the gums; shortness of breath; and/or weightloss. AML is one of the most common types of leukemia among adults and is rarely diagnosed in people under age 40. There are many potential causes of AML such as certain blood disorders, inherited syndromes, environmental exposures, and drug exposures; however, most people who develop AML have no identifiable risk factor.
Who are the top Acute Myeloid Leukemia (AML) Local Doctors?
Marcos J. De Lima
Elite in Acute Myeloid Leukemia (AML)
Dr. Marcos J. De Lima
Hematology Oncology | Oncology | Hematology
Elite in Acute Myeloid Leukemia (AML)
Dr. Marcos J. De Lima
Hematology Oncology | Oncology | Hematology

Osu Internal Medicine LLC

410 W 10th Ave, 
Columbus, OH 
614-293-8000
Languages Spoken:
English
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Accepting New Patients

Marcos De Lima is a Hematologist Oncology specialist and an Oncologist in Columbus, Ohio. Dr. De Lima is rated as an Elite provider by MediFind in the treatment of Acute Myeloid Leukemia (AML). His top areas of expertise are Acute Myeloid Leukemia (AML), Leukemia, Myelodysplastic Syndrome (MDS), Bone Marrow Transplant, and Bone Graft. Dr. De Lima is currently accepting new patients.

David A. Rizzieri
Elite in Acute Myeloid Leukemia (AML)
Dr. David A. Rizzieri
Oncology
Elite in Acute Myeloid Leukemia (AML)
Dr. David A. Rizzieri
Oncology

Novant Health Cancer Institute - Elizabeth (Hematology)

125 Queens Road, Suite 610, 
Charlotte, NC 
980-302-6600
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

David Rizzieri is an Oncologist in Charlotte, North Carolina. Dr. Rizzieri is rated as an Elite provider by MediFind in the treatment of Acute Myeloid Leukemia (AML). His top areas of expertise are Acute Myeloid Leukemia (AML), Leukemia, Myelodysplastic Syndrome (MDS), Bone Marrow Aspiration, and Bone Graft. Dr. Rizzieri is currently accepting new patients.

 
 
 
 
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Stephen J. Forman
Elite in Acute Myeloid Leukemia (AML)
Dr. Stephen J. Forman
Hematology
Elite in Acute Myeloid Leukemia (AML)
Dr. Stephen J. Forman
Hematology

City Of Hope Medical Foundation

1500 Duarte Rd, 
Duarte, CA 
626-256-4673
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Stephen Forman is a Hematologist in Duarte, California. Dr. Forman is rated as an Elite provider by MediFind in the treatment of Acute Myeloid Leukemia (AML). His top areas of expertise are Non-Hodgkin Lymphoma, Acute Myeloid Leukemia (AML), Graft Versus Host Disease (GvHD), Bone Marrow Transplant, and Bone Marrow Aspiration.

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What are the latest Acute Myeloid Leukemia (AML) Clinical Trials?
A Phase I/II Study of Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination With Quizartinib in Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)
A Phase I/II Study of Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination With Quizartinib in Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)
Who is this study for: Adult patients with Acute Myeloid Leukemia
Enrollment Status: Recruiting
Publish Date: December 17, 2025
Intervention Type: Drug
Study Drugs: Liposomal Daunorubicin, Liposomal Cytarabine, Quizartinib
Study Phase: Phase 1/Phase 2

Summary: This phase I/II trial studies the side effects and best dose of CPX-351 in combination with quizartinib for the treatment of acute myeloid leukemia and high risk myelodysplastic syndrome. CPX-351, composed of chemotherapy drugs daunorubicin and cytarabine, works in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them fr...

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A Measurable Residual Disease (MRD) Driven, Phase II Study of Venetoclax Plus Chemotherapy for Newly Diagnosed Younger Patients With Intermediate Risk Acute Myeloid Leukemia: A Tier 1 MYELOMATCH Clinical Trial
A Measurable Residual Disease (MRD) Driven, Phase II Study of Venetoclax Plus Chemotherapy for Newly Diagnosed Younger Patients With Intermediate Risk Acute Myeloid Leukemia: A Tier 1 MYELOMATCH Clinical Trial
Enrollment Status: Recruiting
Publish Date: December 17, 2025
Intervention Type: Procedure, Drug
Study Phase: Phase 2

Summary: This phase II MyeloMATCH treatment trial compares cytarabine with daunorubicin versus cytarabine with daunorubicin and venetoclax versus venetoclax with azacitidine for the treatment of younger patients with intermediate risk acute myeloid leukemia (AML). Cytarabine is a drug that inhibits some of the enzymes needed for deoxyribonucleic acid (DNA) replication and repair and can slow or stop the gr...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center