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Learn About Proteus-Like Syndrome

What is the definition of Proteus-Like Syndrome?
Proteus-like syndrome describes people who do not meet the diagnostic criteria for Proteus syndrome but who share many of the characteristic signs and symptoms associated with the condition. Affected people may experience some of the following features: overgrowth of the bones, skin, and other tissues; hamartomas; abnormalities of the skin, blood vessels (vascular tissue) and fat (adipose tissue); and distinctive facial features. Approximately 50% of people with Proteus-like syndrome are found to have changes in the PTEN gene. In these cases, the inheritance is autosomal dominant.
Who are the top Proteus-Like Syndrome Local Doctors?
Endocrinology | Medical Genetics | Pediatrics
Endocrinology | Medical Genetics | Pediatrics

University Of Wisconsin Medical Foundation Inc

1500 Highland Ave, 
Madison, WI 
Languages Spoken:
English
Accepting New Patients

Kim Keppler-Noreuil is an Endocrinologist and a Medical Genetics provider in Madison, Wisconsin. Dr. Keppler-Noreuil and is rated as an Elite provider by MediFind in the treatment of Proteus-Like Syndrome. Her top areas of expertise are Proteus Syndrome, Proteus-Like Syndrome, Acromicric Dysplasia, and Hemihyperplasia. Dr. Keppler-Noreuil is currently accepting new patients.

Medical Genetics | Pediatrics
Medical Genetics | Pediatrics
49 Convent Dr Rm 4a56, 
Bethesda, MD 
Languages Spoken:
English

Leslie Biesecker is a Medical Genetics specialist and a Pediatrics provider in Bethesda, Maryland. Dr. Biesecker and is rated as an Elite provider by MediFind in the treatment of Proteus-Like Syndrome. His top areas of expertise are Proteus Syndrome, Proteus-Like Syndrome, Acromicric Dysplasia, and Lenz Microphthalmia Syndrome.

 
 
 
 
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Rome, IT 

Giuseppe Zampino practices in Rome, Italy. Zampino and is rated as a Distinguished expert by MediFind in the treatment of Proteus-Like Syndrome. His top areas of expertise are RASopathies, Costello Syndrome, Cardiofaciocutaneous Syndrome, and Noonan Syndrome.

What are the latest Proteus-Like Syndrome Clinical Trials?
The Phenotype and Etiology of Proteus Syndrome

Summary: This study will examine rare congenital disorders that involve malformations and abnormal growth. It will focus on patients with Proteus syndrome, whose physical features are characterized by overgrowth, benign tumors of fatty tissue or blood vessels, asymmetric arms or legs, and large feet with very thick soles. The study will explore the genetic and biochemical cause and course of the disease, t...

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A Multi-Cohort Phase 2 Dose-Escalation Study of MK-7075 (Miransertib) in Proteus Syndrome

Background: Proteus syndrome is a rare overgrowth disorder. Most people begin to have symptoms between 6 months and 2 years of age. There are very few living adults with this disease. There is also no known treatment for it. Researchers want to see if a new drug can slow down or stop overgrowth in people with Proteus syndrome.

Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center