Thyroid Cancer Overview
Learn About Thyroid Cancer
Thyroid cancer is a cancer that starts in the thyroid gland. The thyroid gland is located in the front of your lower neck.
Tumor - thyroid; Cancer - thyroid; Nodule - thyroid cancer; Papillary thyroid carcinoma; Medullary thyroid carcinoma; Anaplastic thyroid carcinoma; Follicular thyroid cancer
Common conditions include: Anaplastic Thyroid Cancer, Follicular Thyroid Cancer, Papillary Thyroid Cancer
Thyroid cancer can occur in people of any age.
Radiation to the thyroid increases the risk of developing thyroid cancer. Exposure may occur from:
- Radiation therapy to the neck (especially in childhood)
- Radiation exposure from nuclear plant disasters
Other risk factors are a family history of thyroid cancer and chronic goiter (enlarged thyroid). Being overweight or having obesity may be a risk factor for papillary carcinoma of the thyroid.
There are several types of thyroid cancer:
- Anaplastic carcinoma (also called giant and spindle cell cancer) is the most dangerous form of thyroid cancer. It is rare, and spreads quickly.
- Follicular carcinoma is more likely to come back and spread.
- Medullary carcinoma is a cancer of non-thyroid hormone-producing cells that are normally present in the thyroid gland. This form of thyroid cancer tends to occur in families.
- Papillary carcinoma is the most common type, and it usually affects women of childbearing age. It spreads slowly and is the least dangerous type of thyroid cancer.
Symptoms vary depending on the type of thyroid cancer, but may include:
- Cough
- Difficulty swallowing
- Enlargement of the thyroid gland
- Hoarseness or changing voice
- Neck swelling
- Thyroid lump (nodule)
Treatment depends on the type of thyroid cancer. Treatment of most thyroid cancer types is effective if diagnosed early.
Surgery is most often the initial treatment. All or part of the thyroid gland may be removed. If your provider suspects that the cancer has spread to lymph nodes in the neck, these will also be removed. If some of your thyroid gland remains, you will need follow-up ultrasound and possibly other studies to detect any regrowth of thyroid cancer.
Radiation therapy may be done with or without surgery. It may be performed by:
- Taking radioactive iodine by mouth
- Aiming external beam (x-ray) radiation at the thyroid
After treatment for thyroid cancer, you must take thyroid hormone pills for the rest of your life. The dosage is usually slightly higher than what your body needs. This helps keep the cancer from coming back. The pills also replace the thyroid hormone your body needs to function normally.
If the cancer does not respond to surgery or radiation, and has spread to other parts of the body, chemotherapy or targeted therapy may be used. These are only needed by a small number of people.
Mskcc Surgery Group
Ian Ganly is an Otolaryngologist in New York, New York. Dr. Ganly is rated as an Elite provider by MediFind in the treatment of Thyroid Cancer. His top areas of expertise are Thyroid Cancer, Papillary Thyroid Cancer, Medullary Thyroid Carcinoma, Thyroidectomy, and Laryngectomy.
MD Anderson
Mark Zafereo is an Otolaryngologist in Houston, Texas. Dr. Zafereo is rated as an Elite provider by MediFind in the treatment of Thyroid Cancer. His top areas of expertise are Anaplastic Thyroid Cancer, Thyroid Cancer, Medullary Thyroid Carcinoma, Thyroidectomy, and Laryngectomy.
New York University
Kepal Patel is a Surgical Oncologist and a General Surgeon in New York, New York. Dr. Patel is rated as an Elite provider by MediFind in the treatment of Thyroid Cancer. His top areas of expertise are Thyroid Cancer, Thyroid Nodule, Follicular Thyroid Cancer, Parathyroidectomy, and Thyroidectomy.
You can ease the stress of illness by joining a cancer support group. Sharing with others who have common experiences and problems can help you not feel alone.
Complications of thyroid cancer may include:
- Injury to the voice box and hoarseness after thyroid surgery
- Low calcium level from accidental removal of the parathyroid glands during surgery
- Spread of the cancer to the lungs, bones, or other parts of the body
Contact your provider if you notice a lump in your neck.
Awareness of risk (such as previous radiation therapy to the neck) can allow earlier diagnosis and treatment.
Sometimes, people with family histories and genetic mutations related to medullary thyroid cancer will have their thyroid gland removed to prevent cancer.
Background: * Endocrine neoplasms (tumors) are among the fastest growing tumors in incidence in the United States. Furthermore, it is often difficult to distinguish between benign or malignant tumors in cancers of the thyroid, parathyroid, adrenal gland, and pancreas. More research is needed to improve detection and treatment options for patients who develop these kinds of cancer. * Researchers are interested...
Summary: The purpose of this phase II study is to find out what effects cabozantinib (XL184) has, good and/or bad, in patients whose tumors one of the following gene changes RET, ROS1, or NTRK fusion, or increased MET or AXL activity. A phase II study looks at how effective a medication is at treating a specific type of cancer and collects information on the side effects of the study treatment. RET, ROS1, ...
Published Date: February 28, 2024
Published By: Sandeep K. Dhaliwal, MD, board-certified in Diabetes, Endocrinology, and Metabolism, Springfield, VA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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National Cancer Institute website. Thyroid cancer treatment (PDQ) - health provisional version. www.cancer.gov/cancertopics/pdq/treatment/thyroid/HealthProfessional. Updated April 11, 2024. Accessed May 7, 2024.
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Thompson LDR. Malignant neoplasms of the thyroid gland. In: Thompson LDR, Bishop JA, eds. Head and Neck Pathology. 3rd ed. Philadelphia, PA: Elsevier; 2019:chap 25.